WebCIB2 and CIB3 bind to TMC1/2 through a domain in TMC1/2 flanked by transmembrane domains 2 and 3. The co-crystal structure of the CIB-binding domain in TMC1 with CIB3 … WebMar 29, 2024 · HIV-1 replication, specifically viral entry, requires CIB1 and CIB2 expression as shRNA knockdown of each impairs replication in Jurkat and primary CD4+ T cells. …
Spatiotemporal Live-Cell Analysis of Photoreceptor Outer Segment ...
WebIn this study, three other members of this protein family (CIB2-4: CIB2, CIB3, and CIB4) were purified and subsequently characterized using biophysical and structural … WebJun 29, 2024 · CIB2 and its homologue, CIB3, modulate the activity of the MT complex and bind to the TMC-1 subunit 12, 14 . Consistent with the role of CIB2 and CIB3 in MT channel function, mutants of CIB2 are ... howm old can u get a job at in australia
10518 - Gene ResultCIB2 calcium and integrin binding
WebApr 12, 2024 · The paraventricular nucleus of the thalamus (PVT) is involved in drug addiction–related behaviors, and morphine is a widely used opioid for the relief of severe pain. Morphine acts via opioid receptors, but the function of opioid receptors in the PVT has not been fully elucidated. Here, we used in vitro electrophysiology to study neuronal … WebApr 12, 2024 · Activity-dependent changes in protein expression are critical for neuronal plasticity, a fundamental process for the processing and storage of information in the brain. Among the various forms of plasticity, homeostatic synaptic up-scaling is unique in that it is induced primarily by neuronal inactivity. However, precisely how the turnover of synaptic … WebFeb 26, 2024 · Calcium- and integrin-binding protein 2 (CIB2) is a small EF-hand protein capable of binding Mg2+ and Ca2+ ions. While its biological function remains largely unclear, an increasing number of studies have shown that CIB2 is an essential component of the mechano-transduction machinery that operates in cochlear hair cells. Mutations in … how moisturizing is sunflower oil